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In Vitro Fertilization IVF

In Vitro Fertilization IVF:

In vitro fertilization IVF is one of the infertility treatments that helps patients to fertilize and reduces the risk of genetic disorders in newborn.  During IVF mature eggs are extracted from ovaries and manually fertilized by retrieved sperm samples in a laboratory. The fertilized egg or embryo is placed inside the uterus to increase the chance of pregnancy.

The full cycle of IVF takes about three to four weeks. The IVF procedure could be perform by using couple’s own egg and sperm or it could involve using eggs and/or sperm from a donor. In some rare cases IVF procedure may require a surrogate uterus for the embryo to be transferred into.

The success rate of IVF depends on various factors including the age of the couple undergoing the procedure and the cause of infertility. IVF treatment is time-consuming and expensive but also is a proper procedure that greatly increases the success rate of pregnancy.

Why IVF is done?

In vitro fertilization IVF is a relatively invasive procedure recommended to those who were unsuccessful with other less invasive treatments such as medication. IVF is considered as a primary treatment for women over age 40. IVF can also be done when you have some specific health conditions, such as:

  • Fallopian tube damage or blockage
  • Ovulation disorders
  • Endometriosis
  • Uterine fibroids
  • Previous tubal sterilization or removal
  • Impaired sperm production or function
  • Unexplained infertility
  • Preventing genetic disorders from being transmitted to the child
  • Fertility preservation in cancer treatments or other health conditions

 

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Best methods of infertility treatment

Best methods of infertility treatment:

Nowadays due to advances in medical sciences and various methods for infertility treatment, the joy of having a child is within the reach of almost anybody. Medical treatments along with assisted reproduction techniques has improved the chance for many men and women with infertility problems to have children. This article gives you useful information about prominent methods of infertility treatment.

The process of infertility treatment:

After various diagnostic tests, different methods of infertility treatment will be applied in accordance with the cause of infertility. After explaining each method and its success rate, doctor provides the couple with different treatment options to choose the one that suits them the most regarding their situation and preferences.

  • In vitro fertilization or IVF:

IVF is a prevalent method to treat infertility problems and consisted of a complex series of procedures. During IVF, after stimulating ovaries and ovulation, mature eggs are retrieved from ovaries and fertilized by sperm outside the uterus in a lab. After the conception of embryo in the lab, the embryo is then placed inside the uterus.

This method is usually offered in conditions where sperm can’t reach the egg naturally, such as blocked fallopian tubes, pelvic adhesions, low sperm count or low sperm mobility.

  • Intrauterine insemination IUIDuring intrauterine insemination IUI which is a simple and painless procedure to facilitate fertilization, the sperm is placed inside the uterus. For IUI to work(hazf) , the fallopian tubes need to be healthy. In this method the egg is not retrieved from ovaries and the process of ovulation and conception occurs naturally.
  • Ovulation stimulation by advanced protocols:
  • Ovulation stimulation is helpful for women with irregular ovulation, ovulation disorder or polycystic ovary (PCO) and mostly used to increase the quantity and quality of eggs and boost the chance of fertilization. There are medications that induce the same effect on egg quality and quantity which are known as ovulation induction medicine.
  • Micro injection or intracytoplasmic sperm injection ICSI
  • Micro injection is an infertility treatment method that a sperm cell is injected directly into the cytoplasm of an egg and cultivate it for a specific period of time in an incubator. After conception and cell division, embryo is made.
  • In vitro maturation IVM:
  • With IVM, instead of increasing follicle growth in body (metaphase 2), immature eggs are extracted from ovaries using a vaginal sonography. Afterwards, extracted eggs are grown in a laboratory and fertilized before being replaced into the womb.
  • Gamete intrafallopian transfer GIFT:
  • GIFT method is mostly used in cases of surrogate womb and is similar to IVF in terms of egg retrieving and sperm preparation. Afterwards, the egg along with adequate amount of sperm are placed directly into the fallopian tubes using a laparoscope.

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IVF: success rate

IVF: success rate

What is IVF success rate in Iran?

IVF success rate is an important point you should notice before performing IVF.

IVF is an infertility treatment technique for infertile couples with appropriate and high success rate in Iran compared to other countries.

 

What is IVF success rate in Iran compared to other countries?

Fortunately, Iran has a lot of experience in infertility treatment science with high IVF success rate compared to countries all over the world and many patients travel to Iran to treat their infertility problems every year.

To evaluate IVF success rate, patients are divided into 2 groups: women age less than 35 years old and women age more than 35 years old.

The success rate of IVF in first group (women <35 y/o) is approximately 40 % and the success rate of IVF in second group (women > 35 y/o) is 15- 20% on average.

IVF success rate differs in fertility clinics and centers depend on many factors.

IVF success rate in Iran is equal or more than global statistics.

IVF in Iran has affordable costs which make Iran an attractive destination for infertility treatment and medical travelers.

High medical care experiences along with fair prices highlight Iran as a leading destination for infertility treatment all over the world.

What affects IVF success rate?

IVF is a technique to treat infertility problems such as sperm count, shape or motility problems or insufficient egg production.

IVF is done in special laboratory environment and many factors affect IVF success rate which mentioned as below:

 

 

Age:

First and most important factor affecting the success rate of IVF is age. The older you get, the lower your chance of successful IVF. In younger people, the chance of access to fresh and young egg and sperm is higher.

Previous successful pregnancy:

If you had a successful pregnancy previously, the success rate of IVF is more for you compared to others.

The reason of infertility:

Infertility reason affects the IVF success rate. IVF success rate decreases in some infertility causes.

Donated egg quality:

If the woman has an ovulation problem, the solution is using donated egg.

Young and fresh eggs have more success rate.

Life style:

Some daily habits have a negative impression on IVF success rate including smoking, obesity, high daily stress, etc.

Infertility clinic quality:

Experienced fertility specialists and embryologists along with high-tech laboratory equipment will increase IVF success rate to a great extent.

Iran is an attractive destination for IVF & infertility treatment regarding all positive points we explained.

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IVF : Infertility treatment

IVF : Infertility treatment:

 

as medical science has been advancing substantially, infertility treatment success rate increased over years. Many men and women with fertility problems have been treated successfully through well-known and reliable methods verified by infertility specialists.  Actually with current state of infertility treatment, there is absolutely no fertility problem that is not curable through existing methods. Iran is one of the pioneers in treating infertility for men and women. To learn more about these methods, some of main approaches to infertility treatment are explained below.

Common methods of infertility treatment:

Given the main cause of infertility, there are various options to treat fertility problems. Treatment usually begins with methods with lowest risk and in case of lack of progress, other methods would be applied.

  • Medication:

In some cases, infertility is caused by disorderliness of hormonal balance or reduction of hormonal storage. In these situations, treatment would be sought through medication. Taking fertility medicines can effectively improve the function of reproductive organs in men and women. Even in some occasions that the cause of infertility is unknown, it is possible to achieve natural fertilization by taking medication.

  • IUI:

Another treatment for infertility is intrauterine insemination IUI. This method involves placing sperm samples inside woman’s uterus helping sperm to reach fallopian tubes thus increasing the chance of fertilization. This method is applied when sperm is unable to reach to the eggs.

  • Surgery

Another approach to infertility treatment is laparoscopy or other extensive abdominal operations. This approach is pursued when infertility is caused by blocked fallopian tubes or diseases such as uterine fibroids, ovarian cysts, endometriosis or anatomical problems in genitals.

  • Assisted reproduction techniques:

In cases where infertility is caused by low sperm count or blocked fallopian tubes, the treatment is very exceptional. It’s called In Vitro Fertilization or IVF. IVF is used only when other treatments proved to be ineffective. In this method infertility specialist collects sperm and egg and unites them in a laboratory using advanced equipment, a process that naturally occurs inside fallopian tubes. IVF is one of the prevailing methods for infertility treatment and assisted reproduction techniques.

 

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IVF : history of IVF in Iran

IVF : history of IVF in Iran

The history of IVF in Iran has been shaped by the interaction between the pioneers of IVF and an interdisciplinary group of experts, together with the endorsement and strong support of the Shia jurists.

  • 1992 – Birth of the first baby following retrograde ejaculation using intrauterine insemination (IUI) first started in 1989 in Aban Hospital by Dr. Jalil Pakravesh (personal communication).
  • 1994 – Birth of the first baby resulting from intracytoplasmic sperm injection (ICSI) and the birth of the first baby through egg donation carried out in Yazd by Dr. Mohmmad-Hossein Amir Arjomand (personal communication).
  • 1996/97–Use of ICSI + percutaneous epididymal sperm aspiration (PESA) resulting in the birth of a baby at Shariati Hospital, Tehran, carried out by Dr. Hojat-Allah Saeedi (personal communication).
  • 1998–First case of transferring an embryo produced from testicular spermatozoon by microinjection carried out by Dr. Akhondi (the author).
  • 2004–Birth of the first baby born following pre-implantation genetic diagnosis (PGD) Royan Institute, Tehran, carried out by Dr. Leila Karimian (personal communication).

Indeed, the use of IVF in a range of contexts such as PGD(more…) (as a preventive measure for diseases with a genetic basis or for sex selection); sperm, egg and embryo donation; surrogacy; fertility preservation; and animal conservation (freezing of egg, sperm and embryo), are commonplace in Iran.

 

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